Corpus Christi Bay is a scenic semi-tropical bay on the Texas coast found in San Patricio and Nueces counties, next to the major city of Corpus Christi. It is separated from the Gulf of Mexico by Mustang Island, and is fed by the Nueces River and Oso Creek from its western and southern extensions, Nueces Bay and Oso Bay. The bay is located approximat…Corpus Christi Bay is a scenic semi-tropical bay on the Texas coast found in San Patricio and Nueces counties, next to the major city of Corpus Christi. It is separated from the Gulf of Mexico by Mustang Island, and is fed by the Nueces River and Oso Creek from its western and southern extensions, Nueces Bay and Oso Bay. The bay is located approximately 136 miles south of San Antonio, and 179 miles southwest of Houston.