Immvention Therapeutix is partnering with Novo Nordisk to develop oral treatments for sickle cell disease (SCD) and other ...

Sickle cell disease is a group of inherited red blood cell disorders characterised by the presence of abnormal hemoglobin, called hemoglobin S. When a person has SCD, their blood cells become ...

When someone inherits two mutant copies of the hemoglobin gene, the abnormal form of the hemoglobin protein causes the red blood cells to lose oxygen and warp into a sickle shape during periods of ...

New data from a Phase 1b clinical trial testing Fulcrum's pociredir for sickle cell disease are expected by the middle and ...

High white cell count, low hemoglobin and oxyhemoglobin desaturation ... large-vessel disease, and perfusion abnormality on neuroimaging. As well as investigating the role of genes and the ...

Unlike adult hemoglobin, FH consists of two α-globin ... Nature 180, 326–328 (1957) ——. Abnormal human haemoglobins. III. The chemical difference between normal and sickle-cell haemoglobins.