Scientists have unveiled insights into how HIV-1, the virus responsible for AIDS, skillfully hijacks cellular machinery for its own survival. By dissecting the molecular interplay between the virus ...

Enhancement of HIV-1 Infectivity. Early work on this topic has ... protein other than CD4 that blocks the function of Env in the virion. Nef enhances infectivity by downregulating this unknown ...

The resulting complex of viral cDNA and virion proteins, now referred to as the pre-integration complex (PIC), is transported to the nucleus (Fig. 1). Figure 1: Models of flap-dependent HIV ...

You have full access to this article via your institution. To demonstrate the power of PCR–mediated recombination and provide an example of the general utility of the method, we constructed ...