While research has uncovered many details about how blood cells function within bone marrow, the work of other cells existing in that space has remained a relative mystery. Now, researchers from the ...
mouse stromal cells and human dermal fibroblasts did not elicit this effect. These preclinical data suggest that unrelated, human bone marrow-derived, culture-expanded MSCs may improve the outcome ...
Researchers have uncovered a hierarchical structure of immune-privileged stem cells in bone marrow niches, revealing their ...
High-potential human mesenchymal stem cells ... Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction. N Engl J Med 2006; 355: 1199–209. e18.
The team tackled a critical challenge in treating multiple myeloma-a blood cancer where malignant plasma cells accumulate in bone marrow, leading to debilitating bone lesions in 80% of patients.
a “conditioning” course of a highly toxic chemotherapy called busulfan required to eliminate diseased cells from the bone marrow and make room for the genetically modified cells. Gene editing ...