The Eagles played without wide receivers AJ Brown and DeVonta Smith, who were sidelined by a hamstring injury and a concussion, respectively. Right tackle Lane Johnson also missed the game because of a concussion. During the game, the Philadelphia offense lost wide receiver Johnny Wilson and center Cam Jurgens.

Philadelphia will head into the Week 5 bye with a 2-2 record after a disastrous 33-16 loss to the Buccaneers. The Eagles exited the first quarter with zero yards of total offense. Following the second loss to Tampa in a year, Hurts took responsibility for the lackluster performance.