Doctors noticed that patients who had sickle cell anemia, a serious hereditary blood disease, were more likely to survive malaria, a disease which kills some 1.2 million people every year.

Researchers described a promising new approach for using gene therapy to treat sickle cell disease in the journal Human Gene ... and sub-tropical regions where malaria is or was common.

Can we predict that natural selection will weed out genetic disease over ... occurrence of the sickle-cell mutation in a region historically hyperendemic for malaria (Kulozik et al., ...

The R21/Matrix-M malaria vaccine offers the highest efficacy in the history of malaria vaccine development as reported by Mehreen Datoo and colleagues.1 The potential for saving the lives of African ...

Was the presence of malaria somehow selecting for the sickle cell allele by felling people who did not inherit it? The fact that sickle cell disease is far less common in the United States ...

We can do better. We can build a system that provides coordinated high-quality care to every patient who needs it.

protects you from malaria. So you really see sickle cell disease wherever you see malaria. And then you might say, well, we don't have malaria in the United States, so why do we have sickle cell ...

Individuals with sickle cell disease—a chronic illness where misshapen, sticky blood cells clump together, reducing oxygen ...

“Sickle cell disease impacts mostly people of Black or African descent. And we believe this is because, many many years ago, ...

Dr. Joseph Lubega calls sickle cell disease “probably the saddest story of a health problem that you could imagine.” He and ...

“The vast majority of people with sickle cell disease come from Afro-Caribbean backgrounds. This is because in sub-Saharan Africa, where malaria is a huge killer, having sickle cell trait (where ...