NFL bettors are counting on a big game for Brandon Aiyuk in light of all the injuries around him. See who else is drawing betting attention in the market.

Rated No. 3 in total DVOA, the Chargers don’t turn it over and they run the ball down their opponents’ throat. Their also No. 1 in defensive DVOA. Take the points and L.A. to start off 3-0. Minnesota is a tough place to play, just ask Brock Purdy.

The Los Angeles Rams managed to score just one touchdown last week against the Cardinals, giving them only three touchdowns in two games. It could be challenging to find the end zone again this weekend against a good 49ers defense and with the team’s top two receivers,

The bruised and battered San Francisco 49ers will need these five players to step up against the short-handed Los Angeles Rams on Sunday.

The 49ers and Rams meet in NFC West action, but both teams are going to look like shells of its best form. Injuries have taken its toll on both the 49ers and R

After dominating the New York Jets in Week 1, it looked like the San Francisco 49ers were once again going to breeze to the best record in the NFC West, earn a comfortable matchup in the playoffs, and go on another deep playoff run in the pursuit of another Lombardi Trophy.

The San Francisco 49ers are going to be missing several key offensive playmakers this week against the Los Angeles Rams. That said, the defense was expecting to get a big boost from the return of safety Talanoa Hufanga.