Fig. 1 | Eliminating tumors with macrophage–drug conjugates. ICD, immunogenic cell death. The process is enhanced by the drug component, which directly kills cancer cells and creates debris for ...

One of their key attributes is their mobility to sites of inflammation, infection, and tumors. This trait garnered the attention of researchers who developed therapies to leverage macrophages’ ...

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.

Researchers from Moffitt Cancer Center have found a new way to boost cancer immunotherapy by targeting a protein called macrophage receptor with collagenous structure, or MARCO. Their study, published ...

Researchers from Moffitt Cancer Center have found a new way to boost cancer immunotherapy by targeting a protein called macrophage receptor with collagenous structure, or MARCO. Their study ...

Carisma Therapeutics is developing a unique, differentiated immuno-oncology (IO) treatment for solid tumors based on chimeric antigen receptor macrophages (CAR-M). Current IO treatments have ...

Colorectal cancer (CRC) is the third most common malignancy and the second leading cause of cancer-related deaths worldwide.

M1 Macrophage-Derived Exosomes: These vesicles exhibit anti-tumor properties by delivering miRNAs that inhibit oncogenic ...