This did not escape two of Mayfield's big media fans, Fox sideline reporter Erin Andrews and studio host Charissa Thompson.

Analyzing NFL Week 11 betting odds and lines, with expert predictions and picks of the 3 best underdogs to cash in on.

We went 4-1 straight up on our top five picks, but 1-4 against the spread. The Baltimore Ravens defeated the Cincinnati ...

While it’s certainly a positive that the reigning Offensive Player of the Year is back in their lineup, the club now has to ...

Star pass-catcher George Kittle and the San Francisco 49ers face the Seattle Seahawks on Sunday at 4:05 p.m. ET, at Levi’s ...

San Francisco treaded water without Christian McCaffrey. Now that the NFL's reigning Offensive Player of the Year is back, it ...

After last week’s games, I’m quite convinced destiny has already chosen the AFC and NFC representatives for this year’s Super Bowl.

San Francisco 49ers head coach Kyle Shanahan has kept his team in the fight for the NFC West title. But he had to address ...

Asked how it must have felt for Moody to go from the 49ers' biggest loser to the hero of the show, Kyle Shanahan broke down ...

Listen in as players from the 49ers locker room shared their excitement for DB Deommodore Lenoir's five-year contract ...

The San Francisco 49ers are preparing for their Week 11 contest against the Seattle Seahawks on Sunday at Levi's Stadium in ...

The San Francisco 49ers earned a hard-fought victory on Sunday against the Tampa Bay Buccaneers, securing back-to-back wins ...