There are several subtypes of iGluR, of which the AMPA receptor (AMPAR) is specialized to initiate signal transduction in the postsynaptic neuron rapidly after binding to glutamate 2. The ...

McGill University researchers have demonstrated that AMPA receptors (AMPARs), which mediate fast excitatory neurotransmission ...

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Therefore, our results suggest that Rab10 inhibits AMPAR trafficking during synaptic potentiation and NMDAR-dependent inactivation of Rab10 facilitates LTP induction. On the contrary, Rab4 promotes ...