Typically, LNPs contain four main lipid components: ionizable lipid that binds to the negatively charged RNA and assists in endosomal escape; phospholipids to provide structural integrity; cholesterol ...
Lipid nanoparticles (LNPs) represent one of the most significant advances in drug delivery technology, offering safe and effective delivery of nucleic acid cargo with flexibility for various ...
Buffer Specificity of Ionizable Lipid Nanoparticle Transfection Efficiency and Bulk Phase Transition
Department of Chemical and Geological Sciences, University of Cagliari & Center for Colloid and Surface Science (CSGI), Cittadella Universitaria, 09042 Monserrato, CA, Italy ...
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