and that the average HIV-1 generation time, defined as the time from release of a virion until it infects another cell and causes the release of a new generation of viral particles, is $2.6$ days.

Scientists have unveiled insights into how HIV-1, the virus responsible for AIDS, skillfully hijacks cellular machinery for its own survival. By dissecting the molecular interplay between the virus ...

Enhancement of HIV-1 Infectivity. Early work on this topic has ... protein other than CD4 that blocks the function of Env in the virion. Nef enhances infectivity by downregulating this unknown ...

The resulting complex of viral cDNA and virion proteins, now referred to as the pre-integration complex (PIC), is transported to the nucleus (Fig. 1). Figure 1: Models of flap-dependent HIV ...

You have full access to this article via your institution. To demonstrate the power of PCR–mediated recombination and provide an example of the general utility of the method, we constructed ...

Prophylactic vaccines remain the best approach for controlling the human immunodeficiency virus-1 (HIV-1) transmission. Despite the limited efficacy of the RV144 trial in Thailand, there is still no ...

We compared the top ranked predicted HIV-Human PPI pairs with the partial positive pairs ... genes that have been reported in the siRNA screen to have an effect on HIV-1 infection upon silencing [1] ...