Researchers have identified cellular factors that regulate the delivery and stability of mRNA to expand the potential of mRNA therapeutics.

A team of researchers has uncovered a key cellular mechanism that affects the function of mRNA vaccines and therapeutics. Their study provides the first comprehensive understanding of how mRNA ...

In endosomes, the ionizable lipid becomes protonated to fuse with the endosomal membrane and release the encapsulated RNA into the cytoplasm for successful translation (in case of mRNA delivery) (Wang ...