AlphaGalileo25d
An Upgraded Nuclease Prime Editor Platform Enables High-Efficiency Singled or Multiplexed Knock-In/Knockout of Genes in Mouse and Sheep Zygotes
Key findings from the study include: Enhanced Prime Editing Efficiency with uPEn: The upgraded nuclease prime editor (uPEn) incorporates a ubiquitin variant (i53) to enhance double-strand break (DSB) ...
C&EN5d
RNA G-Quadruplex Reprogramming with Guanine-Rich Antisense Oligonucleotides Inhibits Monoamine Oxidase B’s Translation
Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Herein, a new rG4 located in the 5′UTR of the MAOB mRNA was ...
eLife26d
Opposing Regulation of TNF Responses and IL-1β+ Macrophages by PGE2-cAMP and IFN-γ Signaling
The pellet was resuspended in a transposase reaction mix consisting of 25 µl 2× TD buffer, 2.5 µl transposase (Illumina), and 22.5 µl nuclease-free water. The transposition reaction was carried out ...
C&EN3d
Optimization of Capillary Vibrating Sharp-Edge Spray Ionization for Native Mass Spectrometry of Triplex DNA
Department of Chemistry, West Virginia University, Morgantown, West Virginia 26506, United States ...
GitHub10d
Security: Yranshevare/carbon_footprinting
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