A systematic literature review found no evidence to support that physical exertion without rhabdomyolysis (muscle breakdown) or heat injury can cause sudden death for individuals with sickle cell ...

In sickle cell disease, a gene mutation causes the hemoglobin molecules in red blood cells to form a rigid chain. This causes the cells to stiffen into a sickle shape, clogging blood vessels and ...

Base editing utilizes enzymes to modify single amino acids at the most foundational unit of DNA, called a base.

Abnormal cells can clog blood vessels, leading to severe pain episodes and restricting oxygen delivery to vital organs ...

We can do better. We can build a system that provides coordinated high-quality care to every patient who needs it.

Jan. 17, 2025 — A new study has found older-looking brains in adults with sickle cell disease, helping to explain the cognitive challenges experienced by such individuals. A brain image from a ...

Immvention Therapeutix is partnering with Novo Nordisk to develop oral treatments for sickle cell disease (SCD) and other ...

People with sickle cell disease often struggle with memory, focus, learning and problem solving, setting them back in ...

Individuals with sickle cell disease – a chronic illness where misshapen, sticky blood cells clump together, reducing oxygen ...

A new study has found older-looking brains in adults with sickle cell disease, helping to explain the cognitive challenges experienced by such individuals. A brain image from a healthy individual ...

Stem cell transplant in young adults and adolescents with severe sickle cell disease may be a feasible option, according to a ...