The San Francisco 49ers can breathe a sigh of relief following the latest update on Isaac Guerendo’s injury status. However, ...

A first-round tender would cost the 49ers an estimated $7,279,000 for the 2025 season according to Over the Cap. The ...

San Francisco 49ers rookie RB Isaac Guerendo suffered MCL and ankle sprains against the Arizona Cardinals, avoiding an ACL ...

San Francisco 49ers running back Isaac Guerendo was forced to exit Sunday's game against the Arizona Cardinals during the ...

The San Francisco 49ers’ practice schedule began a day later than normal with a Monday night showdown against the Detroit ...

Unfortunately, San Francisco 49ers' running back Isaac Guerendo was carted off the field early in the first quarter.

The 49ers lost their standout rookie Isaac Guerendo in scary fashion. What update did the running back provide Monday?

Rookie Isaac Guerendo battled injuries himself after taking the lead role in the backfield, and was carted off during the ...

While the Lions are preparing to make a deep run in the playoffs, the 49ers have lost their last two games and have dropped ...

San Francisco 49ers running back Isaac Guerendo is set to return from foot and hamstring injuries and play Monday vs. the ...

Jahmyr Gibbs and Isaac Guerendo will be the featured fantasy football running backs on Monday Night Football in Week 17.

The Week 17 edition of Monday Night Football may not mean much for either the San Francisco 49ers or Detroit Lions, but it means plenty for bettors and fantasy ...