Greg Papa joins "49ers Talk" host Matt Maiocco and discusses if 49ers wide receiver Brandon Aiyuk will step up in Rams ...

The 49ers revealed their status reports Friday for their injured players ahead of Sunday’s visit to the Los Angeles Rams.

San Francisco 49ers star tight end George Kittle missed his second straight practice on Friday as ESPN insider Adam Schefter ...

The San Francisco 49ers placed running back Christian McCaffrey on injured reserve on Aug. 14 but have yet to fill his vacant ...

The 49ers revealed their status reports Friday for their injured players ahead of Sunday’s visit to the Los Angeles Rams.

Brock Purdy has faced the Vikings twice in his career. In both games, he turned the ball over twice, led the 49ers to just 17 ...

Week 3 matchup vs. Rams with key injuries to McCaffrey, Samuel, and Kittle, testing their depth in this crucial NFC West ...

The San Francisco 49ers are officially listing tight end George Kittle as doubtful to play for their Week 3 divisional ...

The 49ers are without Christian McCaffrey, Deebo Samuel and maybe George Kittle, while the Rams won’t have top receivers ...

The San Francisco 49ers will face the Los Angeles Rams on Sunday without wide receiver Deebo Samuel and running back ...

The San Francisco 49ers certainly have had some bad luck so far this season and are dealing with some high-profile injuries.

Injuries are piling up for the 49ers as they gear up for a critical showdown against the Rams. Head coach Kyle Shanahan ...