After three straight seasons of long playoff runs, the San Francisco 49ers are packing up and heading home early for a change ...

The San Francisco 49ers just lost 47-24 to the Arizona Cardinals. Here are the 49ers' grades for this performance. QUARTERBACK: D Joshua Dobbs t ...

Jauan Jennings’ ejection and Isaac Guerendo’s cart-off knee injury added to the 49ers’ season-long macabre in Sunday’s 47-24 ...

There wasn’t much to play for when the San Francisco 49ers and Arizona Cardinals suited up Sunday at State Farm Stadium. The ...

Kyler Murray threw for 242 yards and four touchdowns, two to Greg Dortch, and the Arizona Cardinals beat the injury-depleted San Francisco 49ers 47-24.

In his absence, Trent Taylor is a candidate to see an increase in workload with San Francisco ... 49ers will entrust the run game in Patrick Taylor and FB Kyle Juszczyk for the rest of their ...

Kyler Murray threw a season-high four touchdowns in a 47-24 blowout of the 49ers on Sunday in the season finale for both teams. Arizona finishes 8-9, while San Francisco goes 6-11. Murray completed 25 ...

One year after coming three points short of a championship in Super Bowl LVIII, the San Francisco 49ers aren't returning to the playoffs and will own a losing record. But change will not be coming ...

Josh Dobbs will start the season finale for the Niners. Dobbs went 3-of-4 for 35 yards and ran for a seven-yard touchdown against Detroit. He will be the third quarterback to start for the 49ers this ...

Jared Goff threw three touchdown passes and the Detroit Lions tuned up for their Week 18 division showdown against Minnesota ...

New York has won four Super Bowls and eight combined championships. The Giants have also sent 32 players to the Pro Football ...