Dual blocking SHP2 and FGFR2 can not only promote the targeted tumor-killing effects and overcome FGFR2 inhibitor resistance caused by feedback activation, but also activate T cell-mediated anti-tumor ...

At the core of this advancement lies a process involving peripheral blood mononuclear cells from dogs, a type of white blood cell. These cells, combined with cytokines and cell markers of both human ...

Plasmacytoid dendritic cells (pDC) primarily function as weak antigen-presenting cells (APC), but have also been shown to ...

The cells that are targeted in the blood are known as peripheral blood mononuclear cells (PBMCs). They are “pushed back in time to an earlier time before they became differentiated into heart or ...

Novel CD37 antibody-drug conjugate shows promise in targeting the Achilles’ heel of acute myeloid leukemia cells.

Researchers report the ability of tofacitinib to reduce infection risk with SARS-CoV-2 in individuals who are deficient in ...

A new discovery in blood immune cells has put researchers one step closer to identifying a blood biomarker that would allow ...

All sequencing data have been deposited in public, open access repository of the Genome Sequence Archive for Human ... peripheral blood represents the main highway for the immune system for RA, SLE ...

Innovative research has provided compelling evidence that perceived stress can directly trigger the relapse of psoriatic skin ...

Binding affinity was assessed using Fortebio. Human peripheral blood mononuclear cells (PBMCs) were cocultured with molecules to test the antibody-dependent cellular cytotoxicity (ADCC) potency. IFN-α ...