One major challenge in making these improved lipids was the difficulty of creating branched ionizable lipids—key components of LNPs that change their charge to help them escape the endosome.

One major challenge in making these improved lipids was the difficulty of creating branched ionizable lipids -- key components of LNPs that change their charge to help them escape the endosome.

One major challenge in making these improved lipids was the difficulty of creating branched ionizable lipids - key components of LNPs that change their charge to help them escape the endosome.

One major challenge in making these improved lipids was the difficulty of creating branched ionizable lipids ... a patent application related to the structure of the BEND lipids and biological ...

Laboratory of Precision Nanomedicine, Shmunis School of Biomedicine and Cancer Research, Tel Aviv University, Tel Aviv-Yafo 69978, Israel Department of Materials Sciences and Engineering, Tel Aviv ...

One significant obstacle in creating these improved lipids was synthesizing branched ionizable lipids, essential components of LNPs that alter their charge to facilitate endosomal escape.

"Dyslipidemia" refers to an abnormality within the lipid profile, encompassing a variety of disorders relating to elevations in total cholesterol, LDL, or TG, or conversely, lower levels of HDL.