"This is important for understanding why fibrosis begins in IPF patients," says Moro. "Many basic researchers and pharma ...

Replicating liver fibrosis is a key element in any in vitro NASH model, however, it is normally poorly assessed, unquantifiable and has a limited dynamic range. An advanced three-dimensional (3D) ...

This review provides a detailed examination of experimental mouse models used to study liver fibrosis regression, both in ...

The three key functions of the Core are listed below: These CF mouse models produce no functional Cftr mRNA or protein, and are particularly useful to stufy consequences of the electrophysiological ...

The murine physiology laboratory has developed models that allow the evaluation of genetic interventions in cardiac function, response to load, inflammation, fibrosis and repair. The common strategy ...

Inhibiting the HIF2 protein was found to promote repair processes in a mouse model of lung injury, and may be a strategy for ...