Fatty acid synthase, the enzyme responsible for fatty acid production in cells, may be a therapeutic target for IPF, a mouse ...

Nanoparticles (NPs) are versatile tools in various applications, particularly in the biomedical fields. To understand their behavior within biological systems, it is crucial to measure their ...

Should I buy an older model for less money? Is the "Pro" model worth it? And should I spring for the iPhone SE in 2025? That's because the iPhone lineup is more convoluted than ever, with Apple ...

Denifanstat, an oral fatty acid synthase (FASN) inhibitor, has emerged as a unique contender in the NASH treatment arena. The drug's mechanism of action directly targets fibrosis ... discount rate in ...

Multiply your mouse’s DPI x Mouse Sensitivity, and aim for a total between 2,000 and 6,000 eDPI. Tweak your eDPI within this range until you are happy with how it feels. A lower eDPI will make ...

Although the bleomycin-induced mouse model has been recognized as the best-characterized model of lung fibrosis with highly relevant pathobiology, there are also some limitations. For example, as we ...

World models, also known as world simulators, are being touted by some as the next big thing in AI. World models take inspiration from the mental models of the world that humans develop naturally.

(G-I) Loss of Slc39a5 improves fibrosis in mice upon NASH dietary challenge ... glucose monitoring system by sampling blood from the lateral tail vein. Homeostatic model assessment of insulin ...

autoimmune hepatitis (AIH), and non-alcoholic steatohepatitis (NASH). This leads to the activation of hepatic stellate cells (HSCs) and excessive ECM deposition (118). Continued progression of liver ...

Pulmonary fibrosis is a disease where there is scarring of the lungs—called fibrosis—which makes it difficult to breathe. This is because the scarring causes the tissues in the lungs to get thick and ...

Denifanstat, an oral fatty acid synthase (FASN) inhibitor, represents a unique mechanism of action in the NASH treatment arena. The drug has shown promising results in Phase 2b trials, particularly in ...