Ashley Byrne - Genentech | LinkedIn
My research focused on harnessing long-read technology for understanding the transcriptome both on a single cell and bulk level to further understand basic cell biology,...
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- Location: Genentech
Ashley Byrne - Google Scholar
Genentech - Cited by 1,770 - Single Cell Transcriptomics - RNA Biology - Nanopore Sequencing - Immunology - Molecular Biology
People | Vollmers Lab - UCSC
Dr. Ashley Byrne. Graduation Fall 2019. Position after graduation: Scientist at Genentech. Honey Mekonen. Specialist at CZ Biohub. Previous Undergraduate Researchers.
Single-cell long-read targeted sequencing reveals ... - Nature
Aug 12, 2024 · Here we develop Single-cell Targeted Isoform Long-Read Sequencing (scTaILoR-seq), a hybridization capture method which targets over a thousand genes of interest, improving the median number of...
Identifying and quantifying isoforms from accurate full-length ...
Jul 17, 2023 · In this manuscript, we introduce and benchmark Mandalorion v4.1 for the identification and quantification of full-length transcriptome sequencing reads. It further improves upon the already strong performance of Mandalorion v3.6 used in …
Nanopore Day, Bay Area 2023 | Oxford Nanopore Technologies
Sep 19, 2023 · Join us for Nanopore Day, Bay Area, to hear the latest tech updates and developments from top researchers using nanopore technology. Presentations cover whole-genome sequencing, single-cell RNA sequencing, methylation and structural variant detection, transcriptomics, plasmid and AAV sequencing.
Single-cell long-read targeted sequencing reveals ... - PubMed
Aug 12, 2024 · Here we develop Single-cell Targeted Isoform Long-Read Sequencing (scTaILoR-seq), a hybridization capture method which targets over a thousand genes of interest, improving the median number of on-target transcripts per cell by 29-fold.
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Accurate long-read transcript discovery and quantification at …
Dec 1, 2023 · Accurate detection and quantification of mRNA isoforms from nanopore long-read sequencing remains challenged by technical noise, particularly in single cells.
Fibroblastic FLT3L supports lymph node dendritic cells in the ...
Aug 16, 2024 · Grem1 FRCs co-localize with DCs and express FLT3L in human and mouse lymph nodes. Using a new genetic model, we provide evidence that FLT3L produced by GREM1 FRCs maintains lymph node preDCs, cDCs, and plasmacytoid DCs (pDCs).
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